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Flow Cytometric Intracellular 5-Methyl Cytosine Expression and Its Correlation With Cytogenetics and Measurable

Sreejesh Sreedharanunni1, Prabhjot Kaur1, Sudhanshi Raina1

  • 1Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

International Journal of Laboratory Hematology
|December 11, 2024
PubMed
Abstract

No abstract available in PubMed .

Keywords:
5‐methyl cytosinePh‐positive ALLflow‐cytometryfluorescence in situ hybridizationmeasurable residual disease

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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