Related Experiment Videos
Xeroderma pigmentosum: oldest living survivor?
Plastic and Reconstructive Surgery
|January 1, 1985
Summary
Xeroderma pigmentosum, a rare genetic disorder causing DNA repair deficiency, typically shortens lifespan. This report details an exceptionally long-surviving patient, highlighting disease heterogeneity and potential for extended survival.
Area of Science:
- Genetics
- Molecular Biology
- Dermatology
Background:
- Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder.
- Characterized by defective DNA repair, leading to extreme sun sensitivity and premature skin aging.
- XP has significant genetic heterogeneity with six complementation groups.