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Adiponectin receptor 1-mediated basolateral amygdala-prelimbic cortex circuit regulates methamphetamine-associated

Zhigang Chen1, Susu Tang1, Xiangyi Xiao2

  • 1College of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.

Cell Reports
|December 11, 2024
PubMed
Summary

AdipoRon (AR) inhibits methamphetamine (MA) reward memories by targeting the BLA-PrL circuit. This pathway, involving AdipoR1 and p-AMPK/Cav1.3 signaling, offers a potential therapeutic target for MA use disorders.

Keywords:
AdipoR1CP: Molecular biologyCP: Neurosciencebasolateral amygdalamethamphetamineprefrontal cortexreward memory

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