Eosinophils were Significantly Elevated in the Chronic Subdural Hematoma Fluids: Two Case Reports

Area of Science:

• Neurosurgery
• Hematology

Background:

• Chronic subdural hematoma (CSDH) is a common neurosurgical condition in the elderly, often treated with burr-hole drainage.
• Microscopic examination of drainage fluid is a standard laboratory analysis for CSDH patients.

Observation:

• Cranial MRI confirmed CSDH in patients.
• Routine blood tests showed no significant abnormalities.
• Postoperative drainage fluid analysis revealed a notable increase in eosinophils.

Findings:

• A significant proportion of eosinophils were observed in the postoperative drainage fluid of CSDH patients.
• No concurrent abnormalities were detected in peripheral blood tests.

Implications:

• The precise mechanism and clinical significance of eosinophil infiltration in CSDH are currently unknown.
• Further investigation into eosinophil and chemokine distribution in CSDH patients' blood and drainage fluid is warranted.
• Understanding eosinophil roles may improve CSDH treatment strategies and recurrence prediction.