JoVE - Journal of Visualized Experiments
JoVE Visualize
Contact Us

Multiple Aneurysms: Insight through the Mirrors

  • 0Nantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France, pacome.constantditbeaufils@chu-nantes.fr.
Neuroepidemiology +

|

December 11, 2024

|

December 11, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Mirror intracranial aneurysms (MIAs) predominantly occur in females and are uniquely associated with the middle cerebral artery (MCA). This suggests a focal vulnerability in MCA locations for patients with multiple intracranial aneurysms (IAs).

Area Of Science

  • Neurosurgery
  • Vascular Neurology
  • Radiology

Background

  • Mirror intracranial aneurysms (MIAs) are bilateral, symmetrical intracranial aneurysms (IAs) on the circle of Willis.
  • This study investigated MIA characteristics and prevalence in a large international cohort with multiple IAs.

Discussion

  • Middle cerebral artery (MCA) location was the sole independent predictor of MIA status.
  • No significant clinical differences were observed between MIA and non-MIA patients.
  • The findings suggest a potential focal vulnerability in MCA locations for developing MIAs.

Key Insights

  • 33.5% of patients with multiple IAs had MIAs, predominantly in females.
  • MCA location is significantly associated with MIA status.
  • MIAs may represent a distinct condition linked to anatomical predisposition.

Outlook

  • Further research into the anatomical factors predisposing to MCA MIAs is warranted.
  • Enhanced vigilance during IA screening and follow-up for MIAs, especially on the MCA, is recommended.
  • Understanding MIA etiology may refine treatment strategies for complex IA cases.

Keywords: