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Comparison of anticoagulant combinations used in granulocyte apheresis

Bera Omer Ugurlu1, Tulay Karaagac Akyol2, Olgu Erkin Çınar1

  • 1Hacettepe University Medical Faculty, Department of Internal Medicine Division of Hematology, Ankara, Turkey.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|December 11, 2024
PubMed

Our study retrospectively examines the number of granulocytes in the products of donors who donated granulocytes between January 2016 and September 2020 at the Hacettepe University Faculty of Medicine Blood Bank. The effects of acid-citrate-dextrose (ACD), trisodium citrate + hydroxyethyl starch (TCC + HES) and ACD + HES combinations used in the apheresis procedure on the granulocyte count of apheresis products were examined. As a result of study, it was seen that the type of anticoagulant combination used during apheresis significantly affected the number of granulocytes collected.

Keywords:
Acid-citrate-dextroseApheresisGranulocyteHydroxyethyl starchTrisodium citrate

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