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Related Experiment Videos

Comparative angiographic right and left ventricular volumes.

R J Pietras, G T Kondos, D Kaplan

    American Heart Journal
    |February 1, 1985
    PubMed
    Summary
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    Pediatric observations of right and left ventricular volumes and ejection fractions persist into adulthood. Adults with healthy hearts show larger right ventricular volumes but a lower right ventricular ejection fraction compared to the left ventricle.

    Area of Science:

    • Cardiology
    • Human Physiology

    Background:

    • Previous studies established relationships between right and left ventricular volumes and ejection fractions in infants and children.
    • It was unknown if these relationships observed in pediatric populations persist into adulthood.

    Purpose of the Study:

    • To assess if the comparative angiographic volumes and ejection fractions of the right and left ventricles in normal children persist in adult patients.

    Main Methods:

    • Seventeen adult patients with no demonstrable organic heart disease underwent comparative right and left ventricular angiography.
    • Ventricular volumes (end-diastolic and end-systolic) and ejection fractions were calculated for both ventricles.

    Main Results:

    • Both right ventricular end-diastolic and end-systolic volumes were significantly greater than those of the left ventricle (p < 0.03 and p < 0.00005, respectively).

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  • The right ventricular ejection fraction was significantly lower than the left ventricular ejection fraction (p < 0.00005).
  • Right and left ventricular stroke volumes were not significantly different.
  • Conclusions:

    • The relationships between right and left ventricular volumes and ejection fractions observed in pediatric populations appear to persist into adult life.
    • Differences in ventricular compliance, muscle mass, and anatomy may explain the observed volume and ejection fraction disparities between the ventricles.