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Chronic arthropathy in long-term hemodialysis

S Goldstein, E Winston, T J Chung

    The American Journal of Medicine
    |January 1, 1985
    PubMed

    Insights

    Long-term hemodialysis patients often experience joint issues. Prolonged dialysis is linked to progressive joint deterioration and functional decline, even without acute arthritis.

    Area of Science:

    • Nephrology
    • Rheumatology
    • Orthopedics

    Background:

    • Patients on long-term hemodialysis can develop acute arthritis and periarthritis.
    • The long-term effects of hemodialysis on joint structure and function require further investigation.

    Purpose of the Study:

    • To evaluate the long-term consequences of hemodialysis on joint structure and function in patients undergoing treatment for 10 or more years.

    Main Methods:

    • A cohort of 11 patients on long-term hemodialysis was assessed for joint symptoms, physical examination findings, and radiographic abnormalities.
    • Symptoms were evaluated, excluding septic or traumatic causes. Physical examinations focused on range of motion, effusion, crepitus, and deformity. Radiographic analysis included assessments for narrowing, erosions, and calcification.

    Main Results:

    • Eight out of eleven patients reported joint symptoms.
    • Nine patients exhibited physical examination abnormalities, such as decreased range of motion and joint deformity.
    • Nine patients showed radiographic abnormalities, including joint space narrowing, erosions, and calcification. More severe joint disease correlated with younger age and longer dialysis duration.

    Conclusions:

    • Prolonged hemodialysis is associated with progressive deterioration of joint structure and function.
    • This deterioration can occur with or without acute episodes of synovitis.
    • Long-term hemodialysis necessitates monitoring for joint health complications.

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