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Developmental and Cell Fate Analyses Support a Postnatal Origin for the Cortical Collecting System in the Mouse

Riana K Parvez1, Réka L Csipán1, Jing Liu1,2

  • 1Department of Stem Cell and Regenerative Medicine, University of Southern California, Los Angeles, California.

Journal of the American Society of Nephrology : JASN
|December 12, 2024
PubMed
Abstract

No abstract available in PubMed .

Keywords:
acidosisdiabetes insipidusdistal tubuleion transportkidney developmentrenal functionrenal tubular acidosistransgenic mousewater channelswater–electrolyte balance

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The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
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