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Updated: Jun 5, 2025

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
[The value of local antibiotics for foot infection in persons with diabetes]
Abstract:
Diabetes-related foot infections(DFI), including diabetes-related foot osteomyelitis, are generally treated with systemic antibiotics. However, systemic antibiotics are often overused and administered for excessively long periods, making patients more susceptible to multidrug-resistant bacteria. Local antibiotics may be beneficial to DFI patients. This article reviews the advantages and disadvantages, types and clinical evidence of local antibiotics in the treatment of DFI, and points out the research gaps and future research direction in this field. This article aims to provide a reference for clinicians in formulating anti-infectious treatment plans for DFI.
Insights
Local antibiotics offer a promising alternative for treating diabetes-related foot infections (DFI). This review explores their benefits, drawbacks, and clinical evidence, guiding better DFI treatment strategies.
Area of Science:
- Infectious Diseases
- Diabetology
- Pharmacology
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