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The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
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Related Experiment Video

Updated: Jun 5, 2025

Preventing the Spread of Malaria and Dengue Fever Using Genetically Modified Mosquitoes

Preventing the Spread of Malaria and Dengue Fever Using Genetically Modified Mosquitoes

Published on: July 4, 2007

Principles for introducing new genes and species for conservation.

Michael K Schwartz¹, Summer L Dunn², William A C Gendron³

¹USDA Forest Service, Rocky Mountain Research Station, Missoula, MT, USA.

Trends in Ecology & Evolution

|December 12, 2024

Summary

Introducing novel genes and species into ecosystems offers conservation benefits but poses risks. This study proposes comprehensive principles to guide conservation managers in making complex decisions about using new technologies.

Keywords:

assisted colonization conservation introduction conservation translocation ethical considerations genetic engineering synthetic biology

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Last Updated: Jun 5, 2025

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Published on: July 4, 2007

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Area of Science:

Conservation Biology
Synthetic Biology
Ecology

Background:

Introducing new genes and species into ecosystems presents complex decisions for conservation.
Synthetic biology and conservation introductions offer benefits like preventing extinctions but carry ecological risks.
Existing guidelines for new conservation tools are insufficient for emerging technologies.

Purpose of the Study:

To develop comprehensive principles for conservation managers navigating emerging technologies.
To integrate biological, legal, social, cultural, and ethical considerations into decision-making.
To clarify the stakes of action and inaction in high-consequence conservation decisions.

Main Methods:

Combining biological, legal, social, cultural, and ethical considerations.
Developing an inclusive set of principles for conservation managers.
Utilizing decision frameworks to integrate multiple considerations.

Main Results:

A framework of principles is proposed to aid conservation managers.
The principles address the complexities of introducing new genes and species.
Decision frameworks help integrate diverse factors for high-consequence choices.

Conclusions:

Comprehensive principles are needed to guide conservation managers using new technologies.
Integrating diverse considerations is crucial for managing ecological introductions.
Decision frameworks can support complex conservation choices involving emerging tools.