Related Experiment Video
Updated: Jun 5, 2025

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
Published on: May 2, 2017
Association Between Geriatric Nutritional Risk Index and Critically Ill Patients With Pressure Injury: Analysis of
Yilei Zhang1,2, Chuan Qin3, Li Xu4
1Oriental Pan-Vascular Devices Innovation College, University of Shanghai for Science and Technology, Shanghai, China.
Insights
The Geriatric Nutritional Risk Index (GNRI) is a key predictor for preventing pressure injuries (PI) in elderly Intensive Care Unit (ICU) patients. Higher GNRI scores indicate a lower risk of PI development.
Area of Science:
- Geriatric Medicine
- Critical Care Medicine
- Nutritional Science
Background:
- Pressure injuries (PI) are a significant concern in Intensive Care Units (ICUs), affecting critically ill patients.
- Limited research exists on the relationship between the Geriatric Nutritional Risk Index (GNRI) and PI occurrence in this vulnerable population.
Purpose of the Study:
- To investigate the association between the Geriatric Nutritional Risk Index (GNRI) and the incidence of pressure injuries (PI).
- To assess the predictive value of GNRI for PI development in elderly ICU patients.
Main Methods:
- A retrospective, longitudinal, single-centre cohort study involving 5327 elderly ICU patients.
- Utilized GNRI calculations and analyzed covariates including demographics, illness severity, comorbidities, and laboratory values.
- Employed logistic regression, receiver operating characteristic curves, and propensity score modeling, adhering to STROBE-nut guidelines.
Main Results:
- Each unit increase in GNRI was associated with a 3.7% decrease in the likelihood of PI occurrence in a fully adjusted model.
- Patients with no identified nutritional risk (based on GNRI) had a significantly lower incidence of PI compared to at-risk patients.
- The median age of the study population was 76 years, with 43.91% females.
Conclusions:
- The Geriatric Nutritional Risk Index (GNRI) is a significant, independent predictor of pressure injury risk in elderly ICU patients.
- Nutritional assessment using GNRI is crucial for the early identification and prevention of PI in this demographic.
- Highlights the need for integrating nutritional strategies into clinical practice for elderly ICU patients to mitigate PI risk.
Aims And Objectives:
To explore the relationship between the Geriatric Nutritional Risk Index (GNRI) and the occurrence of Pressure injury (PI) in elderly Intensive Care Unit (ICU) patients.
Background:
PI represent a significant health concern within ICU, where the occurrence of such injuries is notably high among critically ill patients. However, few studies have explored the relationship between GNRI and PI.
Design:
A longitudinal, single-centre, retrospective study.
Methods:
The study utilised GNRI calculation to identify PI occurrences. A comprehensive set of covariates was analysed, including demographic information, severity of illness scores, comorbidities, therapeutic interventions, vital signs and laboratory values. Statistical analysis involved descriptive statistics, logistic regression and receiver operating characteristic curves, supplemented by a doubly robust estimation method and propensity score modelling. This study follows the STROBE-nut checklist.
Results:
Among 5327 critically ill patients enrolled in the study, with a median age of 76 years, of which 2339 were females, representing 43.91% of the total study population. Binary logistic regression analysis revealed that with each unit increase in the GNRI, the likelihood of PI occurrence decreased by 3.7% in the fully adjusted model. Furthermore, there was a significant decrease in PI occurrence among patients deemed to have no risk compared to those identified as at-risk.
Conclusions:
GNRI emerges as a significant, independent predictor of PI risk in elderly ICU patients, underscoring the importance of nutritional assessment and management in this population.
Relevance To Clinical Practice:
This study highlights the critical importance of nutritional assessment, specifically through GNRI, in early identification and prevention of pressure injuries among elderly ICU patients, underscoring the need for integrated nutritional strategies in clinical settings.
No Patient Or Public Contribution:
This is a retrospective cohort study, and no patients or the public were involved in the design and conduct of the study.
More Related Videos
04:00Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
Published on: July 26, 2024
10:21Evaluation of Hydration Status by Bioelectrical Impedance Vector Analysis in Patients with Ischemic Heart Disease Undergoing Exercise Stress Test
Published on: September 22, 2023
Related Concept Videos
Current Trends in Nursing I
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Assessment of the Gastrointestinal System II: Health Perception Pattern
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include: