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Updated: Jun 5, 2025
Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
Experience of using electroconvulsive therapy for bipolar disorder: A retrospective study from North India
Sandeep Grover1, Namita Sharma1, Subho Chakrabarti1
1Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Background:
Little information is available on response to electroconvulsive therapy (ECT) in patients with bipolar disorder (BD) from India.
Aim:
This exploratory study aims to evaluate and compare the sociodemographic and clinical profiles, treatment outcomes of BD patients with depression and mania/mixed episode who received ECT and to evaluate the predictors of response to ECT.
Results:
Data of 278 BD patients who received 325 ECT courses were extracted from the ECT register. The number courses of ECT for bipolar depression (n = 202) exceeded those for mania/mixed episodes (n = 123). In terms of response to ECT, >75% response was achieved in 63.3% cases and >50% response was seen in about 90% of the patients. No significant difference was seen in response to ECTs between bipolar depression and mania/mixed episodes.
Conclusion:
The present study suggests that about two-thirds of the BD patients show more than 75% response to ECT, and more than 90% of the BD patients show more than 50% response to ECT.
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