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Application of microscopic smartphone attachment for remote preoperative lab testing.

Kefan Song1,2, Alexander T Adams2,3

  • 1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States.

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A new point-of-care (POC) device offers rapid, accurate lab testing for surgical readiness, improving accessibility for remote patients. This portable diagnostic tool streamlines preoperative exams, enhancing patient care and outcomes.

Keywords:
blood analysishealthcaremicroscopepathologypoint-of-carepreoperative testing

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Area of Science:

  • Biomedical Engineering
  • Medical Diagnostics
  • Point-of-Care Testing

Background:

  • Traditional preoperative testing involves extensive lab work, posing logistical challenges for patients, especially those traveling long distances.
  • These challenges can lead to significant delays and burdens in assessing surgical readiness.

Purpose of the Study:

  • To adapt and validate a previously developed point-of-care (POC) device system for accurate and rapid laboratory testing.
  • To assess the system's compatibility across different mobile platforms (Android to iOS) and its effectiveness in cell image analysis for preoperative assessments.

Main Methods:

  • The POC system was transitioned to an iOS platform with a custom application for optimal image capture.
  • A cell counting algorithm, utilizing Hough circle detection, was refined for automated cell analysis from captured images.

Main Results:

  • The system captured high-quality images with resolutions of 26.3 px/µm and 2.19 µm.
  • The cell counting algorithm achieved high precision (0.8663) and recall (0.9312), demonstrating accurate cell detection and quantification.

Conclusions:

  • The POC device offers a portable, low-cost solution for streamlined preoperative testing, enhancing accessibility for rural or traveling patients.
  • Future developments aim to expand functionality, positioning the device as a viable alternative to traditional lab tests for improved patient care and surgical outcomes.