Related Experiment Video
Updated: Jun 5, 2025

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Expansion of Human Peripheral Blood γδ T Cells using Zoledronate
Published on: September 9, 2011
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Parathyroid Hormone-Mediated Hypercalcemia With Remarkable Bone Mineral Density Recovery After Multiple Zoledronic
Meumbur P Kpughur-Tule1, Carly M Hubers2, Mahvish Renzu1
1Internal Medicine, Trinity Health Oakland/Wayne State University, Pontiac, USA.
Cureus
|December 13, 2024
Summary
Zoledronic acid treatment significantly improved bone mineral density (BMD) in a 95-year-old woman with hypercalcemia and osteoporosis. The therapy was effective and safe, even with co-existing chronic kidney disease (CKD).
Area of Science:
- Geriatric Medicine
- Endocrinology
- Nephrology
Background:
- Hypercalcemia can be associated with parathyroid hormone (PTH) mediated conditions.
- Osteoporosis is a significant concern in the elderly, increasing fracture risk.
- Elderly patients often present with multiple comorbidities, complicating treatment decisions.
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