Primary cutaneous CD4⁺ small/medium T-cell lymphoproliferative disorder nodule successfully treated with laser Co₂...

This case report describes an 83-year-old patient with a history of non-melanoma skin cancer who presented with a violaceous, painless nodule on the neck. Dermoscopic examination and subsequent biopsy revealed a Small/Medium CD4⁺ T-cell lymphoproliferative disorder (SMPLPD) of the skin. Although excision was initially recommended, the patient opted for treatment with CO₂ laser ablation. The procedure had some minor complications but resulted in successful healing. SMPLPDs are a rare skin condition with limited treatment data, and this case suggests that CO₂ laser ablation with minimal margins could be a viable alternative for selected patients, reducing bleeding and promoting second-intention healing for small nodules. However, more extensive follow-up data for SMPLPD cases are needed to understand long-term outcomes better.