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Updated: Jun 5, 2025

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
Published on: May 28, 2021
Command line to pipeLine: Cross-biobank analyses with Nextflow
Anurag Verma1, Zachary Rodriguez2, Lindsay Guare3
1Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA, anurag.verma@pennmedicine.upenn.edu.
Abstract:
Biobanks hold immense potential for genomic research, but fragmented data and incompatible tools slow progress. This workshop equipped participants with Nextflow, a powerful workflow language to streamline bioinformatic analyses across biobanks. We taught participants to write code in their preferred language and demonstrated how Nextflow handles the complexities, ensuring consistent, reproducible results across different platforms. This interactive session was ideal for beginner-to-intermediate researchers who want to (1) Leverage biobank data for genomic discoveries, (2) Build portable and scalable analysis pipelines, (3) Ensure reproducibility in their findings, (4) Gain hands-on experience through presentations, demonstrations, tutorials, and discussions with bioinformatics experts.

