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Updated: Jun 5, 2025

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Induction of Graft-versus-host Disease and In Vivo T Cell Monitoring Using an MHC-matched Murine Model
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Human Genetic GLUT1 Deficiency Results in Impaired T Cellular IFN-γ Production
Renske de Jong1, Anandhi Rajendiran1, Judit Turyne Hriczko1
1Department of Pediatrics, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
European Journal of Immunology
|December 13, 2024
Abstract:
GLUT1 deficiency prevents glucose uptake in T cells resulting in lower intracellular ATP generation and IFNy production.
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