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Computer-generated holography enables high-uniformity, high-efficiency depth-of-focus extension in endoscopic OCT
Optics Letters
|December 13, 2024
Summary
This study introduces a novel method using computer-generated holography and 3D printing to enhance the depth of focus in endoscopic optical coherence tomography (OCT) probes. This innovation improves imaging capabilities inside the human body.
Area of Science:
- Biomedical Optics
- Medical Imaging
- Optical Engineering
Background:
- Endoscopic optical coherence tomography (OCT) enables high-resolution imaging inside the body.
- Current endoscopic OCT faces limitations in probe size, resolution, and depth of focus (DOF).
Purpose of the Study:
- To develop a method for extending the DOF in endoscopic OCT with high uniformity and efficiency.
- To overcome the trade-offs limiting current endoscopic OCT probe designs.
Main Methods:
- Utilized multi-level diffractive optics and computer-generated holography (CGH) for light-field modulation.
- Employed femtosecond laser two-photon 3D printing for direct fabrication on a single-mode fiber, eliminating the need for an objective lens.
Main Results:
- Achieved precise control over the intensity distribution of the OCT probe light.
- Demonstrated extended DOF with high uniformity and efficiency.
- Verified the method's superiority through numerical simulation, beam measurement, and imaging with a home-built system.
Conclusions:
- The developed CGH-based diffractive optic method significantly enhances DOF in endoscopic OCT.
- This approach offers a compact, efficient solution for improved internal body imaging.
- The direct fiber fabrication method simplifies probe construction.
