Related Experiment Video
Updated: Jul 26, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
Published on: November 5, 2016
Construction of antibacterial silicone rubber catheter modified with the biomass carbon dots and its properties
Jing Liu1, Ziyang Shao1, Liyuan Liu2
1College of Textile Engineering, Taiyuan University of Technology, Taiyuan 030024, People's Republic of China.
Abstract:
To endow silicone rubber (SR) catheter with antibacterial property, the SR catheter was modified with a new kind of biomass carbon dots (CDs) by the bulk modification to obtabin the SR/CDs catheter. The antimicrobial behavior and biocompatibility of SR/CDs catheter were analyzed by plate counting method, cytotoxicity test andin vivoanimal experiments. The results showed that, SR/CDs catheter possessed antimicrobial properties, and the minimum inhibitory concentration of SR/CDs catheter was 20 mg ml-1againstEscherichia coliandStaphylococcus aureus. The antimicrobial mechanism of SR/CDs was further investigated, and it was found that the SR/CDs induced the production of reactive oxygen species in bacterial cells by disrupting the bacterial membrane through adsorption. In addition,in vivoexperiments have shown that SR/CDs catheter owns good biosafety profile and reduces the risk of catheter-associated urinary tract infections by modulating inflammatory factors. Meanwhile, SR/CDs catheter can be produced in a simple production process using an extruder, which is expected to be used as a novelty type of catheter in the clinic.
More Related Videos
11:19Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
Published on: May 10, 2018
08:08Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Related Concept Videos
Special Staining Techniques
Bioreactor Controls-I
Production of Antibiotics