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Updated: Jul 31, 2026

Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration
Published on: June 16, 2015
A novel strategy of dysphagia-oriented matrices bovine tendon collagen-cassava starch composite gels
Yuhong Lin1, Zhuo Wang1, Chaoxue Shi1
1College of Food Science and Engineering, Gansu Agricultural University, Lanzhou 730070, China.
Abstract:
Dysphagia foods are designed for individuals with swallowing difficulties to consume safely. Texture-modified diets have become essential in dysphagia management. This study aimed to assess the safety and effectiveness of bovine tendon collagen (BTC) as a texture modifier to alter the starch gel network through a synergistic effect with cassava starch (CS), enhancing its application in dysphagia foods. The results indicated that BTC addition initially reduced gel water retention then increased, with a minimum observed at 2 % BTC. However, all gels demonstrated excellent WHC. The viscoelasticity, hardness, adhesion, gumminess, and thermal stability of composite gels improved with rising BTC concentrations. Secondary structure analysis revealed BTC altered the ordered structures of CS, with hydrogen bonds playing a key role. The microstructure showed that BTC disrupted and attached to the gel network, forming a more compact structure. Additionally, BTC inhibited CS digestion, increasing resistant starch content and decreasing rapidly digestible starch content. Furthermore, International Dysphagia Diet Standardization Initiative tests indicated that 2 % BTC gels could be categorized as level 4 (pureed or extremely thick), while gels with 4-6 % BTC could be classified as level 5 (minced and moist). These findings highlight the potential of BTC-CS composite gels for innovative dysphagia food development.
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