Related Experiment Video
Updated: Jun 5, 2025

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
Published on: January 31, 2025
Rationale for osteoporosis screening in men
Radhika R Narla1,2, Robert A Adler3,4
1Division of Endocrinology, Metabolism, and Nutrition, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
Abstract:
The US Preventive Services Task Force has not recommended osteoporosis screening in men. Department of Veterans Affairs clinicians reviewed the literature on male osteoporosis screening and treatment. They concluded that targeted screening identifies men at risk and osteoporosis drugs reduce fracture risk similarly in men and women.
Purpose/Introduction:
The US Preventive Services Task Force (USPSTF) has found insufficient evidence for recommending for or against osteoporosis screening in men. Department of Veterans Affairs osteoporosis experts reviewed the literature on osteoporosis screening and treatment in men.
Methods:
Although not done systematically, the literature was reviewed by a panel of 20 Department of Veterans Affairs clinicians with extensive experience with osteoporosis in men. Virtual meetings and multiple email communications resulted in a consensus.
Results:
Screening, particularly targeted screening in men, has been found to identify men at risk for fracture. Prior studies have shown osteoporosis drugs have similar effects in men and women. A recent large observational trial demonstrated that hip fracture risk is similarly reduced for both sexes by current medications.
Conclusion:
The consensus of the panel was that targeted screening of men for osteoporosis would lead to greater use of osteoporosis medication, lowering fracture risk.
Insights
Targeted screening for osteoporosis in men can identify those at risk. Osteoporosis medications effectively reduce fracture risk in men, similar to women, supporting broader screening.
Area of Science:
- Gerontology
- Endocrinology
- Public Health
Background:
- The US Preventive Services Task Force (USPSTF) has not established evidence-based guidelines for osteoporosis screening in men.
- Osteoporosis affects men and poses a significant fracture risk, yet screening remains under-addressed.
Purpose of the Study:
- To review the existing literature on osteoporosis screening and treatment specifically in men.
- To establish a consensus among Department of Veterans Affairs (VA) clinicians regarding male osteoporosis management.
Main Methods:
- A literature review was conducted by a panel of 20 experienced VA clinicians specializing in male osteoporosis.
- Consensus was achieved through virtual meetings and extensive email communication.
Main Results:
- Targeted screening effectively identifies men at elevated risk for osteoporotic fractures.
- Pharmacological interventions for osteoporosis demonstrate comparable efficacy in reducing fracture risk for both men and women.
- Recent studies indicate that current osteoporosis medications significantly lower hip fracture risk in men, mirroring effects seen in women.
Conclusions:
- The panel reached a consensus that implementing targeted osteoporosis screening in men would enhance medication utilization.
- Increased use of osteoporosis medications is expected to lead to a reduction in fracture incidence among the male population.
More Related Videos
07:12Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
Published on: September 28, 2017
06:59Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
Published on: September 8, 2023
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Bone Remodeling
Menopause
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Osteoclasts in Bone Remodeling