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Congenital dislocation of the hip in the American black
Insights
Congenital dislocation of the hip (CDH) is less common in black infants than previously thought, with an incidence of 0.46/1000. This finding may suggest genetic differences compared to other populations.
Area of Science:
- Orthopedics
- Pediatrics
- Genetics
Background:
- Congenital dislocation of the hip (CDH) is a condition affecting infants.
- Previous studies suggested a higher incidence in certain populations.
Purpose of the Study:
- To determine the incidence of CDH in black infants.
- To compare CDH rates between black and white infants.
Main Methods:
- Retrospective review of 19 cases of CDH in black infants between 1977 and 1982.
- Calculation of CDH incidence rates per 1000 live births for black and white populations.
Main Results:
- The incidence of complete CDH in the studied black population was 0.46/1000.
- The incidence of complete CDH in the studied white population was 1.5/1000.
- Six cases (31.6%) were atypical CDH associated with other anomalies; 13 cases (68.4%) were typical CDH.
Conclusions:
- The incidence of CDH in black infants is lower than previously reported.
- Observed lower incidence may indicate genetic heterogeneity within populations.
- Further research into genetic factors influencing CDH is warranted.
Abstract:
Between 1977 and 1982, 19 cases of congenital dislocation of the hip (CDH) were encountered in black infants. Six of these cases were associated with other anomalies (atypical CDH); 13 were typical CDH. The incidence of complete CDH in the white population studied is 1.5/1000; in the black population studied it is 0.46/1000. The increased incidence in comparison to previous studies may possibly reflect genetic heterogeneity in the control population relative to the African black.