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Colorectal Cancer (CRC) Screening in Occupational Health Surveillance Exams Is Associated With Decreased CRC
Marianne Cloeren1, John Dement2, Kian Ghorbanpoor1
1Division of Occupational and Environmental Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Colorectal cancer (CRC) screening participation significantly reduced mortality in a screened population. The fecal immunochemical test (FIT) showed the greatest impact, highlighting the importance of occupational health screening programs.
Area of Science:
- Occupational Health
- Preventive Medicine
- Cancer Epidemiology
Background:
- Colorectal cancer (CRC) screening is recommended for adults aged 45-75.
- Examined CRC screening impact in a population with occupational exposures using national screening program data.
Purpose of the Study:
- To evaluate the impact of CRC screening participation on mortality within the Building Trades National Medical Screening Program (BTMed).
- To assess the effectiveness of different screening tests (gFOBT, HS-gFOBT, FIT) over time.
Main Methods:
- Utilized data from BTMed (1998-2021) and the National Death Index.
- Employed standardized mortality ratios (SMRs) to compare participants and nonparticipants.
- Used Poisson and Cox regression for internal impact analyses of CRC screening.
Main Results:
- CRC screening participation rates increased over time: gFOBT (68.2%), HS-gFOBT (78.7%), FIT (85.9%).
- Nonparticipants had a significantly higher CRC SMR (2.04) than participants (1.07).
- Screening reduced CRC mortality by 2% (gFOBT), 12% (HS-gFOBT), and 61% (FIT).
Conclusions:
- Higher CRC screening participation was observed compared to the general population.
- Screening participation significantly reduced CRC mortality, with FIT demonstrating the most substantial impact.
- Occupational health programs should integrate CRC screening due to its significant mortality benefits.
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