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Polysaccharide-based implant drug delivery systems for precise therapy: Recent developments, and future trends
Suraj Kumar1, Rishabha Malviya2, Sathvik Belagodu Sridhar3
1Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Plot No 17 A, Yamuna Expressway, Greater Noida, U.P., India; Pragya College of Pharmaceutical Sciences, Shanti Nagar, Gaya, Bihar, India.
Annales Pharmaceutiques Francaises
|December 15, 2024
Summary
Polysaccharide-based implants offer effective drug delivery with fewer side effects. This review details their development and biomedical applications for targeted therapies.
Area of Science:
- Biomaterials Science
- Drug Delivery Systems
- Polymer Chemistry
Background:
- Implantable drug delivery systems enhance therapeutic efficacy and patient compliance.
- Biopolymers, especially polysaccharides, are crucial for modulating drug release profiles.
- Diverse polysaccharides offer unique properties for fabricating advanced implantable devices.
Purpose of the Study:
- To review strategies for developing polysaccharide-based implants.
- To comprehensively understand the role of various polysaccharides in implant fabrication for targeted therapy.
- To explore biomedical applications and recent advancements in polysaccharide implants.
Main Methods:
- Literature review of polysaccharide-based implantable drug delivery systems.
- Analysis of specific polysaccharides including starch, cellulose, alginate, and chitosan.
- Examination of applications in oral, nasal, bone, and ocular delivery, as well as antiviral therapy.
Main Results:
- Polysaccharides are versatile materials for creating effective implantable drug delivery systems.
- Various polysaccharides like hyaluronic acid and dextran demonstrate significant potential.
- Recent advancements show promise in targeted therapy and diverse biomedical applications.
Conclusions:
- Polysaccharides are highly suitable for developing innovative implantable drug delivery systems.
- These systems offer improved drug administration with reduced side effects.
- Further research into polysaccharide-based implants will advance targeted therapeutic strategies.
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