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Updated: Jun 5, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 15, 2013

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Enhanced dynamic coupling in a nuclear receptor underlies ligand activity

Tracy Yu1, Priscilla Villalona1, Sabab Hasan Khan1

  • 1Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA.

The Journal of Biological Chemistry
|December 15, 2024
PubMed

Keywords:
agonistsallosteric signalingbile acidscoregulatorsfarnesoid X receptormolecular dynamics simulationsnuclear receptorstranscriptonal regulation

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