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[Thymic Carcinoma Operated After Lung Cancer Operation:Report of a Case]
Takehiko Okagawa1, Takaki Fujimura, Ryota Kiriyama
1Department of Thoracic Surgery, Okazaki City Hospital, Okazaki, Japan.
Kyobu Geka. the Japanese Journal of Thoracic Surgery
|December 15, 2024
Summary
A 70-year-old man developed a thymic squamous cell carcinoma, a synchronous double cancer, in the anterior mediastinum after lung cancer surgery. This diagnosis was confirmed through surgical resection and immunostaining.
Area of Science:
- Thoracic Surgery
- Oncology
- Pathology
Background:
- A 70-year-old male patient with a history of lung cancer surgery presented with a new anterior mediastinal nodule.
- Initial positron emission tomography-computed tomography (PET-CT) during lung cancer surgery did not detect this lesion.
Purpose of the Study:
- To investigate the nature of the anterior mediastinal nodule detected on follow-up computed tomography (CT).
- To diagnose and treat the suspected recurrence or new primary tumor.
Main Methods:
- Follow-up CT scan revealed an anterior mediastinal nodule.
- Subsequent PET-CT demonstrated increased standardized uptake value (SUV) max of 5.57 in the nodule.
- Surgical resection via a subxiphoid approach was performed for diagnosis and treatment.
- Immunohistochemical staining for CD5 and CD117 confirmed thymic squamous cell carcinoma.
Main Results:
- The anterior mediastinal nodule was diagnosed as thymic squamous cell carcinoma.
- The patient had a history of a similar carcinoma during previous lung cancer surgery.
- This finding suggests a synchronous double cancer.
Conclusions:
- Thymic squamous cell carcinoma can present as a synchronous double cancer with lung cancer.
- Multimodality imaging and surgical pathology are crucial for accurate diagnosis and management.
