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Dural Venous Sinus Thrombosis: A Rare Cause of Intracranial Hemorrhage
Harris Alam1, Dru Curtis2, Syed A Aftab2
1Radiology, Florida State University College of Medicine, Orlando, USA.
Insights
Dural venous sinus thrombosis (DVST) is a serious condition often linked to trauma. Prompt diagnosis and anticoagulation therapy can lead to full recovery in pediatric patients.
Area of Science:
- Neurology
- Radiology
- Pediatrics
Background:
- Dural venous sinus thrombosis (DVST), a type of cerebral venous thrombosis, presents with significant morbidity and mortality.
- The annual incidence is 3-5 cases per million adults, with predisposing factors aligning with Virchow's triad: venous stasis, hypercoagulability, and endothelial damage.
Observation:
- Risk factors for poor outcomes include female sex, intracranial hemorrhage, infection, and cancer.
- Trauma is a notable risk factor, especially in pediatric cases.
- Initial diagnosis often uses non-contrast CT to rule out hemorrhage, with MRI useful for subacute/chronic cases.
Findings:
- This case highlights extensive post-traumatic DVST in a pediatric patient with characteristic imaging findings.
- The patient experienced complete resolution of symptoms following appropriate diagnosis and treatment.
Implications:
- Early recognition and management of DVST are crucial for favorable outcomes.
- Anticoagulation is the primary therapeutic approach, alongside addressing underlying causes.
- This case underscores the importance of considering DVST in pediatric trauma patients.
Abstract:
Dural venous sinus thrombosis, a subset of cerebral venous thrombosis, is an important pathology due to its significant morbidity and mortality. This process has an annual incidence of three to five cases per million adults. Although copious predisposing factors exist, the core principles revolve around Virchow's triad: venous stasis, hypercoagulability, and vascular endothelial damage. There are various risk factors related to unfavorable outcomes, which include female sex, intracranial hemorrhage, infection, cancer, and more. Trauma tends to be a risk factor, particularly in pediatric populations, as in this patient's case. Initial diagnosis in the acute setting commonly involves non-contrast CT studies to exclude hemorrhage. In subacute or chronic settings, MRI can be utilized. Anticoagulation remains the mainstay of therapy for treatment, along with treating any underlying causes of thrombosis. We present a pediatric patient with extensive post-traumatic dural venous sinus thromboses with classic imaging findings as well as full resolution of clinical symptoms after this pathologic process was recognized and treated appropriately.
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