Related Experiment Video
Updated: Jun 5, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Markedly Exophytic Hypertrophic Lichen Planus in a Patient With Ichthyosis Vulgaris
Jack Catoe1, Andrew Siref2, Christopher Huerter1
1Dermatology, Creighton University School of Medicine, Omaha, USA.
Abstract:
Hypertrophic lichen planus (HLP) is an idiopathic inflammatory condition characterized by hyperkeratotic plaques or nodules, typically occurring bilaterally on the wrists, ankles, or lower extremities. This variant of lichen planus is more common among African-American patients and occupies a broad differential with other keratotic skin conditions, some of which are malignant, making recognition and accurate diagnosis essential. We present an unusual case of a 49-year-old African-American woman with four markedly exophytic, horn-like lesions on her shins, ultimately diagnosed as HLP. Her medical history was also notable for ichthyosis vulgaris. Although no known interaction exists between HLP and ichthyosis vulgaris, the combination of these conditions may have contributed to intense pruritus, leading to increased excoriation. This excoriation could have influenced the unusual growth pattern, as mechanical disruption is associated with increased keratin production in hyperkeratotic conditions.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

