Extra-medullary Plasmacytomas: A Case Series of Rare Hematological Tumors

Solitary plasmacytoma is a rare malignant tumor belonging to the family of plasma cell proliferation. It accounts for a small portion of plasma cell tumors and remains a rare condition. We report three cases of rare extraosseous plasmacytomas in young patients. Case 1 describes a 55-year-old patient with multiple cutaneous plasmacytomas who underwent a watchful waiting approach. Case 2 discusses a 44-year-old patient with nasal plasmacytoma who was successfully treated with exclusive radiotherapy. Case 3 reports on a 52-year-old patient with a solitary ovarian plasmacytoma who underwent surgical resection and did not receive adjuvant treatment due to complete resection. The patients did not have multiple myeloma and had different treatment approaches based on the location and extent of the plasmacytoma. Local recurrence and progression to multiple myeloma may occur, justifying prolonged and rigorous monitoring.