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Updated: May 3, 2026

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Submandibular Ectopic Thymic Mass in a 6-Month-Old Infant.

Jordan Fenner1, Israel Saramago1, Jorge Oldan2

  • 1Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States.

World Journal of Nuclear Medicine
|December 16, 2024
PubMed
Summary

Ectopic cervical thymus in infants is rare and often asymptomatic. This case highlights the use of advanced imaging, including FDG-PET/CT, to diagnose an incidental submandibular mass in an infant.

Keywords:
F-18 FDG PET/CTectopic thymic tissuesubmandibular mass

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Area of Science:

  • Pediatric Radiology
  • Head and Neck Imaging
  • Nuclear Medicine

Background:

  • Ectopic cervical thymus is an uncommon pediatric diagnosis.
  • It can be asymptomatic or present with compressive symptoms like stridor or dysphagia.
  • Standard imaging includes ultrasound and MRI, with biopsy if indeterminate.

Observation:

  • An incidental submandibular mass was discovered on MRI in a 6-month-old infant undergoing evaluation for seizures.
  • The mass was initially identified on a noncontrast MRI.
  • Further workup was initiated to determine the nature of the submandibular mass.

Findings:

  • The submandibular mass was confirmed through radiologic and pathologic evaluation.
  • Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) was employed as part of the diagnostic workup.
  • FDG-PET/CT was utilized to potentially aid in establishing a definitive diagnosis.

Implications:

  • This case demonstrates the utility of FDG-PET/CT in evaluating pediatric neck masses, particularly when standard imaging is inconclusive.
  • It expands the understanding of imaging modalities for ectopic cervical thymus.
  • Highlights the importance of thorough evaluation of incidental findings in pediatric imaging.