Deep-learning-based markerless tracking of distal anatomical landmarks in clinically recorded videos for assessing

Hamid Abbasi1, Sarah R Mollet1, Sian A Williams2,3

  • 1Auckland Bioengineering Institute (ABI), University of Auckland, Auckland, New Zealand, New Zealand.

Insights

Automated infant movement analysis using deep learning can now track distal limb rotations, crucial for early detection of neurodevelopmental disorders like cerebral palsy.

Area of Science:

  • Biomedical Engineering
  • Developmental Neuroscience
  • Medical Imaging

Background:

  • Abnormal General Movements (GMs) in infants are key indicators of neurodevelopmental disorders, such as cerebral palsy.
  • Automated General Movements Assessments (GMA) platforms can enhance early identification of at-risk infants.
  • Previous deep learning models accurately tracked limb longitudinal axes but missed crucial rotational data.

Purpose of the Study:

  • To develop and validate a deep learning model capable of accurately capturing distal limb rotational movements in infants.
  • To improve the accuracy of automated General Movements Assessments (GMA) by incorporating rotational data.
  • To enhance the early detection of neurodevelopmental disorders through advanced infant pose reconstruction.

Main Methods:

  • Utilized a ResNet-152 deep neural network model.
  • Trained the model on 26 diverse videos combining laboratory and clinical data.
  • Focused on improving accuracy for distal limb landmarks, which were previously challenging to track.

Main Results:

  • Achieved >85% accuracy for distal limb landmark tracking.
  • Attained an overall accuracy of 98.28% (SD 2.29) across 24 landmarks.
  • Demonstrated that increased data diversity and sample size improved performance on challenging distal markers.

Conclusions:

  • The developed deep learning scheme effectively captures clinically relevant infant rotational movements.
  • This approach forms a foundation for robust infant pose reconstruction for automated GMA.
  • Improved automated GMA holds significant potential for earlier and more accurate screening of neurodevelopmental disorders.

Related Concept Videos