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Updated: Jun 5, 2025
Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
Published on: May 16, 2022
Metabolic nanoscopy enhanced by experimental and computational approaches
Hongje Jang1, Shuang Wu1, Yajuan Li1
1Shu Chien - Gene Lay Department of Bioengineering, University of California San Diego, La Jolla, CA USA.
Super-resolution microscopy reveals precise molecular distributions in biological samples. This review summarizes techniques and highlights future research directions for nanoscopic chemical analysis.
Area of Science:
- Biophysics
- Molecular Biology
- Microscopy
Background:
- Microscopy advancements drive biological discoveries.
- Super-resolution microscopy offers precise molecular distribution insights.
Purpose of the Study:
- To review techniques for visualizing multiple molecular distributions in biological samples.
- To highlight future collaborative research directions.
Main Methods:
- Review of experimental microscopy techniques.
- Analysis of computational approaches for molecular visualization.
Main Results:
- Detailed summary of current visualization techniques.
- Identification of nanoscopic chemical details in biological samples.
Conclusions:
- Super-resolution microscopy is crucial for understanding molecular organization.
- Collaborative research will advance nanoscopic imaging in biology.
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