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Published on: May 22, 2018
Tokenvizz: GraphRAG-Inspired Tokenization Tool for Genomic Data Discovery and Visualization
Çerağ Oğuztüzün1, Zhenxiang Gao1, Rong Xu1
1Case Western Reserve University, Cleveland, Ohio, USA.
Abstract:
One of the primary challenges in biomedical research is the interpretation of complex genomic relationships and the prediction of functional interactions across the genome. Tokenvizz is a novel tool for genomic analysis that enhances data discovery and visualization by combining GraphRAG-inspired tokenization with graph-based modeling. In Tokenvizz, genomic sequences are represented as graphs, where sequence k-mers (tokens) serve as nodes and attention scores as edge weights, enabling researchers to visually interpret complex, non-linear relationships within DNA sequences. Through a web-based visualization interface, researchers can interactively explore these genomic relationships and extract biologically meaningful insights about regulatory patterns and functional elements. Applied to promoter-enhancer interaction prediction tasks, Tokenvizz outperformed traditional sequential models while providing interpretable insights into genomic features, demonstrating the advantage of graph-based representations for biological discovery.
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