Multifunctional Roles of Sec13 Paralogues in the Euglenozoan Trypanosoma brucei

Mohamed Sharif1,2, Lydia Greenberg3, James Bangs3

  • 1Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, 955 Main Street, Buffalo NY 14203.

Summary

Both Sec13 proteins in Trypanosoma brucei are essential for COPII vesicle transport. This finding challenges the exclusive role of TbSec13.2 in the SEA/GATOR complex, revealing its function in ER export.

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