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Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
Clinical Features of Long COVID Patients Coinfected With Mycoplasma pneumoniae
Xiaodan Zhu1, Yanhua Li2, Jinghua Wang1
1Department of General Practice, The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310000, China.
Abstract:
Background: Since the SARS-CoV-2 pandemic, many patients have suffered prolonged complications, called "long COVID." Mycoplasma pneumoniae is a common respiratory pathogen. Reports of simultaneous long COVID and M. pneumoniae infections are rare in the literature. Methods: We analyzed the clinical data of patients with long COVID-19 who visited the Respiratory Clinic of The Affiliated Hospital of Hangzhou Normal University between January 1 and January 31, 2023, together with their laboratory and radiographic findings, with Pearson's χ 2 test. Results: Fifty-two patients diagnosed with both long COVID and M. pneumoniae infection and 77 with long COVID only were compared. The ages, clinical symptoms, and comorbidities of the two groups did not differ significantly (p > 0.05). However, sex and imaging findings differed between the groups. Conclusions: Our study showed that long COVID-M. pneumoniae coinfection was more commonly seen in females and patients with typical chest computed tomography (CT) images.
Insights
Long COVID patients with Mycoplasma pneumoniae coinfection are more often female and show typical chest CT scans. This finding highlights a specific demographic and imaging pattern for this rare coinfection.
Area of Science:
- Infectious Diseases
- Pulmonology
- Public Health
Background:
- Long COVID, a post-SARS-CoV-2 syndrome, presents prolonged health complications.
- Mycoplasma pneumoniae is a frequent respiratory pathogen.
- Simultaneous long COVID and Mycoplasma pneumoniae infections are infrequently documented.
Purpose of the Study:
- To investigate the clinical characteristics of patients with coexisting long COVID and Mycoplasma pneumoniae infection.
- To compare coinfected patients with those having long COVID alone.
Main Methods:
- Retrospective analysis of clinical data from long COVID patients.
- Inclusion of laboratory and radiographic findings.
- Statistical comparison using Pearson's chi-squared test.
Main Results:
- Fifty-two patients had long COVID with Mycoplasma pneumoniae coinfection; 77 had long COVID only.
- No significant differences in age, symptoms, or comorbidities between groups.
- Significant differences observed in sex distribution and chest imaging findings.
Conclusions:
- Long COVID-Mycoplasma pneumoniae coinfection is more prevalent in females.
- Typical chest computed tomography (CT) findings are associated with this coinfection.
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