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Updated: May 2, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
Sustained improvement of obsessive-compulsive symptoms following interruption of deep brain stimulation
Israel Aristides de Carvalho Filho1, Marcelo Queiroz Hoexter1, Fabio L F Godinho2
1Department of Psychiatry, University of São Paulo, São Paulo, Brazil.
Abstract:
A 59-year-old male with severe treatment-resistant OCD achieved sustained symptom improvement after discontinuing deep brain stimulation (DBS) for over four years. Despite partial relief with ventral capsule/ventral striatum (VC/VS) DBS, complications led to device removal in 2018. Remarkably, the patient remained largely symptom-free, suggesting neuroplasticity changes in dysfunctional neurocircuits. This rare case highlights DBS's role in psychiatry, emphasizing the need for tailored surgical strategies and long-term follow-ups to optimize outcomes and understand DBS mechanisms.
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