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Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

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A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
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Related Experiment Video

Updated: Jun 5, 2025

Generation of Organotypic Raft Cultures from Primary Human Keratinocytes
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Oral Hairy Leukoplakia

Meropi Karakioulaki1, Franziska Schauer1

  • 1University of Freiburg, Freiburg, Germany franziska.schauer@uniklinik-freiburg.de.

The New England Journal of Medicine
|December 16, 2024
PubMed
Summary

No abstract available in PubMed .

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