Long-term outcome following multimodality treatment in a cat with recurrent laryngeal adenocarcinoma

A 9.5-year-old male neutered domestic short-haired cat received two courses of postoperative, definitive-intent conformal radiation therapy (RT) for recurrent laryngeal adenocarcinoma (LACA). Adjuvant RT was prescribed (16 × 3.0 Gy, total 48 Gy) following incomplete resection. Following tumor recurrence and subsequent incomplete resection 31.5 months after the first course, a second course was prescribed (20 × 2.5 Gy, total 50 Gy). Acute and late adverse events were mild. No evidence of local recurrence was documented 42 months following the second course when the cat was euthanized for renal disease. This first report of long-term control in a cat with LACA supports further evaluation of surgery and definitive-intent RT.