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Updated: Jun 4, 2025

The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability
Published on: April 28, 2022
Developing Iron and Iodine Enrichment in Tomato Fruits to Meet Human Nutritional Needs
Nabeel Ahmad Ikram1,2, Muna Ali Abdalla2, Karl H Mühling2
1Department of Agronomy, Muhammad Nawaz Shareef University of Agriculture, Multan 60000, Pakistan.
Abstract:
Iron (Fe) and iodine (I) are essential microelements required for a healthy life, with Fe playing a vibrant role in oxygen transport, and I is vital for cognitive development and thyroid function. Global Fe and I deficiencies affect a significant portion of the population worldwide, leading to widespread health concerns, especially anemia, impaired cognitive function, and thyroid disorders. This review not only inspects the potential of agronomic biofortification to enrich Fe and I content in tomatoes, but also highlights its bright future for crop nutrition. It discusses the latest developments in agronomic biofortification methods focused on improving the enrichment of Fe and I in tomatoes, emphasizing practical approaches such as seed priming, soil application, and foliar spray. Notably, the review explores the promising impacts of Fe and I biofortification on growth, yield, and improved fruit quality in tomatoes. Moreover, it offers an in-depth investigation of the efficacy of agronomic biofortification in enhancing the nutritional contents of tomatoes by combining the most recent research findings. It highlights the impact of agronomic biofortification in mitigating micronutrient deficiencies worldwide and its capacity to encourage sustainable agriculture and improve community health by enhancing crop nutrition.
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