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Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-II: Pathophysiology and Classification01:26

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
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Asthma I: Introduction01:28

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Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
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Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

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Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
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Related Experiment Video

Updated: May 2, 2026

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice
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Monkey dander asthma.

R W Petry, M J Voss, L A Kroutil

    The Journal of Allergy and Clinical Immunology
    |February 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Two patients developed asthma triggered by cotton top tamarin dander, confirmed by IgE antibody testing. This suggests a potential allergic cross-reactivity between New World monkey species.

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    Area of Science:

    • Allergy and Immunology
    • Primatology
    • Pulmonology

    Background:

    • Asthma is a chronic respiratory condition.
    • Exposure to animal dander is a known asthma trigger.
    • New World monkeys, like the cotton top tamarin, are increasingly present in research and zoological settings.

    Observation:

    • Two patients presented with acute asthma symptoms following exposure to cotton top tamarin dander.
    • Both patients exhibited positive results for IgE antibodies to monkey dander via RAST (radioallergosorbent test) and immediate skin prick tests.
    • Antigens in cotton top tamarin urine and dander were found to react with patient IgE.

    Findings:

    • The study identifies IgE-mediated asthma in two patients due to cotton top tamarin dander exposure.
    • Radioallergosorbent testing confirmed specific IgE antibodies against cotton top tamarin allergens.
    • Evidence suggests potential allergenic cross-reactivity between cotton top tamarin and capuchin (another New World monkey) dander.

    Implications:

    • This research highlights a novel asthma trigger in cotton top tamarin dander.
    • Findings suggest the need for increased awareness of potential allergic reactions in individuals with occupational or recreational exposure to New World monkeys.
    • The observed cross-reactivity may have implications for diagnosing and managing allergies across different primate species.