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Related Concept Videos

Infertility in Females01:28

Infertility in Females

275
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
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275
Oogenesis02:07

Oogenesis

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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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Resveratrol and Female Fertility: A Systematic Review.

Alessandro Bertoldo1, Damiano Pizzol2, Dong Keon Yon3

  • 1U.O.S.D. of Assisted Reproductive Technologies "G. Beltrame", Ospedale di Oderzo, ULSS2, 31046 Treviso, Italy.

International Journal of Molecular Sciences
|December 17, 2024
PubMed
Summary
This summary is machine-generated.

Resveratrol may positively impact female fertility by improving ovarian function, according to a review of current scientific literature. Further research is needed to confirm optimal dosage and safety for reproductive outcomes.

Keywords:
3,5,4-trihydroxystilbenefemale fertilityfemale infertilityresveratrol

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Area of Science:

  • Reproductive Biology
  • Nutraceutical Science

Background:

  • Resveratrol, a natural polyphenol, exhibits various health benefits, including potential positive effects on female fertility.
  • Growing evidence suggests resveratrol's therapeutic potential in addressing female infertility.

Approach:

  • Systematic literature review of Medline, PubMed, Web of Science, and Embase databases.
  • Inclusion of 24 studies (9 in vivo, 15 in vitro) investigating resveratrol's effects on female reproductive health.
  • Narrative summary of findings on resveratrol interventions and women's fertility.

Key Points:

  • Resveratrol may improve ovarian function and positively impact reproductive outcomes in women.
  • In vitro studies on human cells and tissues provide insights into resveratrol's mechanisms.
  • Limited but promising evidence suggests a role for resveratrol in managing female infertility.

Conclusions:

  • Current literature indicates resveratrol may play a beneficial role in female infertility, primarily through improved ovarian function.
  • Further studies are essential to determine optimal resveratrol dosage, intake periods, and potential adverse effects on implantation and pregnancy.
  • Resveratrol's potential benefits warrant continued investigation for enhancing female reproductive health.