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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
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Left Ventricular and Atrial Function Analysis Following Transcatheter Edge-to-Edge Mitral Valve Repair
Timor Linder1,2, Doron Sudarsky1, Liza Grosman-Rimon3
1Cardiovascular Institute, Tzafon Medical Center, Poriya 1528001, Israel.
Journal of Clinical Medicine
|December 17, 2024
Summary
Transcatheter edge-to-edge mitral valve repair (Mitral TEER) significantly improves left atrial (LA) function and reduces LA volumes early after the procedure. Speckle tracking echocardiography reveals these rapid functional changes in LA strain.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Cardiology
Background:
- Conventional echocardiography assesses left ventricle (LV) and left atrium (LA) volumes and mitral regurgitation before and after transcatheter edge-to-edge mitral valve repair (Mitral TEER).
- Previous research focused on LV parameter changes and LA reverse remodeling post-Mitral TEER, with limited data on early LA strain changes.
- Understanding early LA functional changes after Mitral TEER is crucial for assessing procedural success and patient outcomes.
Purpose of the Study:
- To evaluate the immediate impact of Mitral TEER on left atrial (LA) strain using speckle tracking echocardiography.
- To assess early changes in LA volumes and global longitudinal strain (GLS) following Mitral TEER.
- To investigate the relationship between Mitral TEER and early functional recovery of the left atrium.
Main Methods:
- A retrospective analysis of 44 patients undergoing Mitral TEER.
- Speckle tracking echocardiography was used to measure LA strain and volumes at baseline and 24-48 hours post-procedure.
- Statistical analysis of demographic, echocardiographic, and clinical characteristics was performed.
Main Results:
- Significant improvement in LA global longitudinal strain (GLS) reservoir post-Mitral TEER (12.2 ± 7 to 14.7 ± 6.4, p = 0.0079).
- Significant reduction in LA maximal and minimal volumes by 17% and 22.5%, respectively.
- Significant improvement in LV GLS (from -9.8% to -12.8%, p < 0.0001), with no significant change in LV stroke volume (p = 0.7798).
Conclusions:
- Successful Mitral TEER leads to very early improvement in left atrial (LA) function.
- Two-dimensional speckle tracking echocardiography is valuable for understanding immediate post-procedural LA functional changes.
- Early assessment of LA strain can provide insights into the effectiveness of Mitral TEER.
Keywords:
left atriummitral regurgitationspeckle tracking echocardiographytranscatheter edge-to-edge mitral valve repairMore Related Videos
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