A Case Report of Atypical Presentation of Metastatic Breast Cancer as Peri-Bronchial Mediastinal Lesion

Breast cancer is the most prevalent cancer among women worldwide. Despite significant advancements in breast cancer treatments over the past decade, late recurrence, a hallmark of breast cancer, remains a major challenge for oncologists. In this case report, we present an atypical presentation of late breast cancer recurrence as a peri-bronchial lesion manifesting as dysphagia 14 years after completing treatment for primary breast cancer. Radiological imaging revealed a peri-bronchial lesion and a subcutaneous nodule in the left mastectomy bed. This case posed a diagnostic dilemma for the attending physicians in distinguishing between late breast cancer recurrence and the possibility of two synchronous primary malignancies. The patient was ultimately diagnosed with metastatic breast cancer with histological confirmation. This case underscores the importance of correlating clinical presentation, radiological images, histopathology examinations and immunohistochemical results to ensure a comprehensive and accurate diagnosis.