Defining a panel of principal bacteria associated with endometritis

Area of Science:

• Gynecology
• Microbiology
• Infectious Diseases

Background:

• Endometritis is a significant uterine condition often linked to bacterial infections.
• Invasive gynecological procedures can increase the risk of developing endometritis.
• Understanding the specific bacterial culprits is crucial for effective treatment and prevention.

Purpose of the Study:

• To compile a comprehensive panel of bacterial genera commonly associated with endometritis.
• To analyze the prevalence of these bacterial genera based on existing literature.
• To explore the etiological factors and diagnostic methods for endometritis.

Main Methods:

• Systematic literature search in PubMed and Web of Science using specific keywords.
• Analysis of 40 studies published over 38 years.
• Identification and quantification of bacterial genera based on citation frequency.

Main Results:

• Identified 31 bacterial genera associated with endometritis.
• The most frequently cited genera were Chlamydia and Ureaplasma (11.03% each), Streptococcus and Mycoplasma (9.56% each), and Enterococcus (8.09%).
• Bacterial infection, often following procedures like curettage or cesarean section, is the primary cause.

Conclusions:

• The identified bacterial panel provides a foundation for understanding endometritis pathophysiology.
• Further research into these microorganisms will clarify their role in the disease.
• Diagnostic techniques like microbial culture and Polymerase Chain Reaction (PCR) are vital for pathogen detection.