Evaluation of the treatment effectiveness in children with coronavirus infection

Olesya M Horlenko1, Khrystyna A Hechko1, Lyubomyra B Prylypko1

  • 1UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE.

Insights

Treatment for children with Coronavirus infection showed positive results, normalizing vitamin D3 and Zinc levels. Inflammatory markers significantly decreased post-treatment, indicating improved health outcomes.

Area of Science:

  • Pediatric infectious diseases
  • Immunology
  • Biochemistry

Background:

  • Coronavirus infection poses significant health risks to children, impacting various physiological markers.
  • Understanding treatment effectiveness is crucial for managing pediatric COVID-19 cases.

Purpose of the Study:

  • To evaluate the effectiveness of a treatment regimen in children diagnosed with Coronavirus infection.
  • To analyze changes in clinical and biochemical parameters following treatment.

Main Methods:

  • A study involving 68 children with confirmed Coronavirus infection, compared to a control group of 28.
  • Analysis of complete blood count (CBC), vitamin D3, Zinc, immunoglobulin levels, and inflammatory markers before and after treatment.

Main Results:

  • Treatment led to positive dynamics in most CBC parameters, except Platelets and Eosinophils.
  • Vitamin D3 and Zinc levels normalized, while immunoglobulin levels showed an initial increase followed by normalization.
  • Significant reductions were observed in inflammatory markers such as IL-1, IL-6, TNF-α, CRP, and D-dimer post-treatment.

Conclusions:

  • The studied treatment is effective in improving clinical and biochemical parameters in children with Coronavirus infection.
  • Treatment helps normalize key indicators and reduce inflammation, contributing to recovery.
  • Further monitoring indicated sustained positive trends and normalization of certain metabolic markers over six months.
Abstract

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