Related Experiment Video
Updated: Jun 4, 2025

04:38
A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
10.2K
Occupational Injury and Suicide in Washington State, Adjusting for Pre-Injury Depression
Katie M Applebaum1, Abay Asfaw2, Paul K O'Leary3
1Department of Environmental and Occupational Health, Milken Institute School of Public Health, The George Washington University, Washington, District of Columbia, USA.
American Journal of Industrial Medicine
|December 18, 2024
Summary
Occupational injuries leading to time off work increased suicide risk in men, even after accounting for pre-injury depression. This highlights the complex link between workplace injuries, mental health, and suicide prevention strategies.
Area of Science:
- Occupational health
- Epidemiology
- Mental health research
Background:
- Previous studies linked occupational injuries to higher suicide rates.
- However, these studies did not account for pre-existing depression.
- This research addresses that gap by examining the role of pre-injury mental health.
Purpose of the Study:
- To investigate the association between occupational injuries and suicide mortality.
- To determine if pre-injury depression influences this relationship.
- To analyze these risks separately for men and women.
Main Methods:
- Linked Washington State workers' compensation injury data (1994-2000) with mortality data through 2018.
- Used competing risks regression to estimate suicide risk for lost-time vs. medical-only injuries.
- Employed quantitative bias analysis (QBA) to adjust for pre-injury major depressive disorder.
Main Results:
- Lost-time injuries were associated with increased suicide mortality in both men and women, adjusting for demographics and earnings.
- After adjusting for pre-injury depression using QBA, the elevated suicide risk remained significant for men (median sHR=1.33).
- The association was not statistically significant for women after adjusting for pre-injury depression.
Conclusions:
- Workplace injuries requiring time off work are linked to increased suicide risk in men, independent of pre-injury depression.
- The interplay between mental health, occupational injury, and suicide is complex.
- Integrating pre-injury mental health data is crucial for future research and prevention efforts.

