Infiltrative Myocardial T-Cell Lymphoma

We report a unique case involving cardiac manifestation of T-cell lymphoma and associated risk management of ventricular arrhythmia and sudden cardiac death. A 39-year-old woman presented with a syndrome consistent with fever in a returned traveler, ultimately diagnosed with stage IV peripheral T-cell lymphoma involving the myocardium with ventricular tachycardia. Management of risk of sudden cardiac death was complicated by hematological management with an antibody-drug conjugate chemotherapy regimen and later autologous stem cell transplant. There was no significant evidence base to consult for management of the present case. Management proceeded on careful multidisciplinary team discussion, risk assessment extrapolated from cardiac sarcoidosis, and consideration of a vulnerable and previously health young patient.