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Autonomic neuropathy associated with autoimmune disease
Neurology
|February 1, 1985
Summary
Autonomic dysfunction can be an early sign of autoimmune disorders, not just nerve damage. This suggests autoimmune conditions should be considered when diagnosing new autonomic disturbances.
Area of Science:
- Neurology
- Immunology
- Autonomic Medicine
Background:
- Systemic vasculitis and autoimmune disorders are known to cause mononeuropathy multiplex and mixed sensorimotor neuropathy.
- Neurologic complications typically involve peripheral nerve damage, such as sensorimotor neuropathies.
Observation:
- Two patients presented with autonomic dysfunction as their primary neurological issue.
- These patients were subsequently diagnosed with underlying autoimmune diseases.
Findings:
- Autonomic dysfunction can manifest as an initial clinical sign of autoimmune disorders.
- This challenges the traditional view of neurologic complications in these conditions.
Implications:
- Autonomic dysfunction should be included in the differential diagnosis for acquired autonomic disturbances.
- Early consideration of autoimmune diseases in patients with autonomic dysfunction may improve diagnostic timelines.
- This highlights the importance of a broader diagnostic approach for autonomic symptoms.
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