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The impact of perceived stress on the prognosis in patients undergoing percutaneous coronary intervention
Qiuyin Shi1, Xuefei Wang2, Dongxia Zhao1
1Department of Cardiology, Zhongda Hospital Affiliated to Southeast University.
Insights
High perceived stress after percutaneous coronary intervention (PCI) significantly increases the risk of major adverse cardiovascular events (MACE). This finding helps identify high-risk patients for closer monitoring post-procedure.
Area of Science:
- Cardiology
- Psychosomatic Medicine
- Clinical Research
Background:
- Percutaneous coronary intervention (PCI) is a common procedure for coronary heart disease.
- Understanding factors influencing post-PCI outcomes is crucial for patient management.
- The role of psychological stress in cardiovascular events requires further investigation.
Purpose of the Study:
- To investigate the association between perceived stress levels and major adverse cardiovascular events (MACE) after PCI.
- To determine if baseline perceived stress predicts short-term MACE occurrence.
Main Methods:
- Prospective cohort study of 339 patients undergoing initial PCI.
- Baseline data collected, including Chinese Perceived Stress Scale (CPSS) scores.
- MACE assessed at 3 and 6 months post-PCI using Kaplan-Meier and Cox regression analyses.
Main Results:
- 16.22% of patients experienced MACE within 6 months post-PCI.
- High baseline CPSS scores were significantly linked to an increased risk of short-term MACE (HR: 6.48, P < 0.05).
Conclusions:
- Elevated perceived stress post-PCI is a significant predictor of short-term MACE.
- Perceived stress levels can aid in identifying PCI patients at higher risk for adverse cardiovascular events.
Objective:
To assess the impact of perceived stress levels in patients undergoing percutaneous coronary intervention (PCI) on the occurrence of major adverse cardiovascular events (MACEs) within a 6-month follow-up period postprocedure.
Methods:
A cohort of 339 hospitalized patients with coronary heart disease undergoing initial PCI was prospectively enrolled in the Department of Cardiology at two branches of Zhongda Hospital Affiliated to Southeast University between January 2022 and July 2022. Baseline data including demographic and clinical characteristics, along with the Chinese Perceived Stress Scale (CPSS), were collected. The occurrence of MACE was evaluated at 3 and 6 months post-PCI. Kaplan-Meier survival analysis and Cox regression models were engaged to analyze the relationship between perceived stress and MACE within 6 months after PCI.
Results:
MACE occurred in 16.22% (55/339) of patients during the 6 following months. High CPSS at baseline was significantly associated with an increasing risk of short-term MACE occurrence (HR: 6.48, 95% confidence interval: 2.98-14.11, P < 0.05).
Conclusion:
High perceived stress during the baseline period after PCI was significantly correlated with increased incidence of MACE within 6 months postprocedure. The perceived stress level could help to identify patients undergoing PCI at heightened risk of short-term MACE.
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